Ownership in AI: Who is responsible for the benefits and downsides of AI’s output?

Constantly evolving and ever more popular, generative AI is being used by more individuals and organisations. Text, digital art, code and even music is being created with the help of Large Language Models (LLMs) and AI chatbots such as ChatGPT. But who is the author, and importantly, who is the owner? Gauri Kohli writes.

Things move quickly in the generative AI world. The fast-paced evolution, backed by the launch of new tools like DALL-E 2, Bard and the recently released GPT-4, however, is creating complex issues surrounding the output generated through these LLMs, such as ownership, attribution and copyrights.
One perspective is that the ownership resides with the companies that invest their resources and expertise in creating these LLMs and that they are responsible for its development. However, LLM users also play a key role in determining the output. They feed in queries, prompts or context that guide the model’s responses. It can be argued that their input is essential in generating the output and thus they must get some level of ownership.

Answering the question of who owns the output is tricky, according to Professor David Epstein, Executive Director, Susilo Institute for Ethics in the Global Economy at the Questrom School of Business, Boston University. “There is no law against integrating things that we have read and interpreting that information and creating a new narrative. And that is what is newly copyrighted,” he says.

“Using that model, as long as ChatGPT does not quote or use sources materially unchanged, then the AI is the owner of that. If a user produces a paper or statement lifted directly or materially unchanged from the AI, then [the AI] should be referenced as the rightful owner of that material.”

Other experts also suggest that the question of ownership is entirely dependent on where you are located. Dr Andres Guadamuz, Reader in Intellectual Property Law at the University of Sussex, notes that in some countries, the outputs have no copyright and they’re in the public domain, whereas in others, the question remains open to interpretation. In the UK, for instance, the output belongs to the person who made it possible for the work to be created.

University of Oxford researchers, in collaboration with international experts, recently published a study in Nature Machine Intelligence addressing the complex ethical issues surrounding responsibility for outputs generated by LLMs. The study, co-authored by an interdisciplinary team of experts in law, bioethics, machine learning and related fields, delves into the potential impact of LLMs in critical areas such as education, academic publishing and intellectual property.

While other studies have focussed primarily on harmful consequences and AI responsibility, the paper diverges. To claim intellectual ownership credit, or authorship for a creation, a person has to put in certain amount of skill and effort, explains the paper’s joint first author Dr Brian D Earp. Therefore, they must also be able to take responsibility for the creation, producing what he sees as a paradox for outputs of human-prompted generative AI.

“Suppose you instruct an LLM to write an essay based on a few keywords or bullet points. Well, you won’t have expended much effort, or demonstrated any real skill, and so as the human contributor to the essay, you can’t really claim intellectual ownership over it,” he says.

“But at the same time, the LLM that actually produced the essay can’t take moral responsibility for its creation, because it isn’t the right kind of agent.”

As a consequence, neither entity can take full ownership of the output. Accordingly, there might be a lot of creative work that is generated in the coming years that will strictly speaking be author-less.

What Dr Earp and fellow joint first author Dr Sebastian Porsdam Mann, with their collaborators, are now considering, is the question of credit or blame for outputs of LLMs that have been specifically trained on one’s own prior. human-generated writing. “We argue that if a human uses a personalised LLM, trained on their own past original writing to generate new ideas or articles, then, compared to using a general-purpose LLM, the human in such a case would deserve relatively more credit and should be able to claim at least partial ownership of the output,” observes Dr Earp.

Can AI replace writers and researchers?
While there are issues with the accuracy and bias of the materials that AI platforms generate, there is growing speculation that these platforms could replace some of the work of writers, analysts, and other content creators. “We need to start considering that an increasing number of works are going to be generated with AI, and short of widespread use of AI detectors, this is a reality that we will have to be content with,” said University of Sussex’s Dr Guadamuz.

Experts like Professor Epstein at Boston University believe it will replace much of the work now done by humans. “All those jobs of writers, analysts and other content creators are at risk, and it is unclear that we will need much more content that would employ those replaced. In other words, it is unlikely that work products will expand at the rate that people are replaced to take up the slack,” he says.

As far as inaccuracies and biases are concerned, ideally humans will provide oversight of the AI content generated to ensure the message they are trying to get out is both accurate and unbiased, or biased in the way they want to communicate their opinions. “People will become the editors of the AI instead of the other way around,” adds Professor Epstein.

Experts are also debating whether LLMs be used for processes and fields which require critical decisions like medical care, legal or finance.

Who gets the blame for damaging content?
As frequent users of generative AI already know, LLMs will at times confidently provide inaccurate or outright false information, known as “hallucinations”. For images, it has also tended to struggle with details like fingers. More sinisterly, however, these tools provide opportunities for fraud and hoaxes.
In March, an image of Pope Francis wearing a white, puffy jacket went viral, and many believed it was real before later discovering it was actually created using AI image generator, Midjourney. A month later, music artist Drake appeared to have another hit single on his hands, except he didn’t write or perform it. An AI doppelganger did.

Who is responsible when generative AI produces unwanted or harmful output, either intentionally or unintentionally, remain open ended. Should the generative AI, it’s company or the user who posed the query be liable?

“I believe that the one who publishes this content is liable, however it is generated. The publisher and author are responsible for what is published now, so that should not change just because it is generated by AI,” says Professor Epstein.

However, Dr Guadamuz, whose main areas of research are artificial intelligence and copyright, says the answer will depend on the situation. In their terms of service, OpenAI claims they’re not liable. With the consistent growth of generative AI and its expanding use, the issue of LLM output and IP ownership is set to grow even more complex.

This article was from the QS Insights Magazine, Issue 3. Read the full edition.

Thammasat launches online Master’s degree program

Thammasat University joins hands with SkillLane to adapt to the future with TUXSA, an online master’s degree program that helps Thammasat University return to being “Digital Academic Marketplace” that meets the needs of the modern world, entering its 4th year of success with more than 16,000 learners, including graduates in 2022.

Nowadays, people’s learning styles have changed, nor does it need to be learned only in the classroom and may not be required to study at university. At the same time, the labor market situation has changed. The research indicates that in the next 5 years, 85 million jobs worldwide will disappear and more than 97 million new jobs will be created, resulting in the new labor market, which may cause the phenomenon of many people being jobless and various emerging jobs do not have the right skilled people to do it. These changes raise important questions: “Is the university still necessary?” and “If the university will continue to survive, how should it adapt and play a role?”

Thammasat University, Thailand’s leading university, has answered these questions by adapting to meet the needs of the future, launching TUXSA, an online master’s degree program that delivers future skills to Thai people. This master’s degree program both meets the learning needs of modern learners and the future labor market at the same time.

Assoc. Prof. Dr. Pipop Udon, Vice President for Academic Affairs, Thammasat University said that Thammasat University is now 88 years old and is very alchemical. However, this alchemy may not catch up with the world. Therefore, we have to go back to being 18 again, as we will meet the needs of the new generation in a technology-driven world. But our working principle is to not investing in anything that you are not proficient in. Instead, find a partner who is good at this. That’s why we’ve teamed up with education technology start-ups to create TUXSA, the online master’s degree with a new way of learning.

The 7 highlights of the TUXSA curriculum are:

– Providing students the opportunity to access the knowledge they need from anywhere at anytime.

– Students are able study only the subjects that interest them.

– If choosing to study the entire course, students will receive a master’s degree with the equivalent honor and privilege as any other general master’s degree.

– Able to plan the cost of studying.

– Saving travel expenses

– Course content developed to meet the needs of learners.

– Able to study while working, maintaining job opportunities

Currently, TUXSA offers 2 courses which are Master of Business Administration Program in Business Innovation (M.B.A. Business Innovation) which has already been acknowledged by the Office of the Ministry of Higher Education, Science, Research and Innovation (MHESI) and Master of Science Program in Digital Business Transformation, majoring in Data Science (M.S. Digital Business Transformation).

“When Thammasat University was established, we were an open university and were accessible to everyone. When we changed to a close university, the number of seats is then limited. People entering Thammasat University have to go through many selection processes. The launch of our TUXSA online master’s degree is considered a “Back to the Future, bringing Thammasat back to its original roots as an academic marketplace, yet technology has pushed us beyond the limitations of seats, time, place and cost. This allows us to respond to new learning needs for people in every generation,” Assoc. Prof. Dr. Pipop concluded.

EdUHK furthers educational collaboration with Cambodia

A delegation led by President Professor Stephen Cheung Yan-leung of The Education University of Hong Kong (EdUHK) met with officials of Cambodia’s Directorate General of Higher Education (DGHE) of the Ministry of Education, Youth and Sport, in Phnom Penh, last month. The purpose of the visit was to follow up on discussions held during DGHE representatives’ visit to EdUHK in February 2023, and to strengthen educational collaboration between the University and the Cambodian Government.

During the meeting, His Excellency Mak Ngoy, Director General of DGHE, and Professor Cheung discussed the potential areas in which EdUHK could contribute to education in Cambodia, such as providing more capacity-building opportunities to in-service teachers in the country, recruiting quality candidates from Cambodia to study on scholarships at the University, and jointly supervising doctoral students. Both parties agreed to further promote educational cooperation, enhance the professional competencies of higher education teachers, and foster collaborative research and knowledge transfer.

On 24 April 2023, Professor Cheung signed a Memorandum of Understanding (MoU) with the Rector of the National University of Battambang (NUBB) His Excellency Sok Khorn. The MoU provides a framework to facilitate strategic education collaboration between the two universities, marking the beginning of a new phase of close cooperation.

His Excellency Sok Khorn expressed his wishes to deepen cooperation with EdUHK, particularly in areas of student and staff exchange, joint research projects, and organising online seminars and workshops for students and staff at NUBB.

Chula’s pledge to be Net Zero by 2050

Chula President pledged to move ahead with greenhouse gas reduction on the Chulalongkorn University campus targeting Net Zero Greenhouse Gas Emission by 2050 and unveiled 5 pilot strategies for minimizing carbon dioxide emissions and also achieving campus sustainability.

Currently, Net Zero Emission is an issue that many countries around the world are focusing on and urgently addressing following the mandate of the United Nations Framework Convention on Climate Change (UNFCCC) 26th Conference on Climate Change (COP26) in 2021. The mandate supports the goal of limiting the global average surface temperature from rising more than 1.5°C to prevent catastrophes caused by extreme weather events.

​“Chulalongkorn University has begun collecting all greenhouse gas emissions data within the university in the academic year 2015 and found that a total of greenhouse gas emissions was 54,955.89 tons of carbon dioxide equivalent (CO2eq), the majority of which resulted from electricity use on campus. This equals 1.21 tons CO2eq emitted per student and personnel that year. Based on this finding, Chula has developed a plan and issued policies and measures to reduce greenhouse gases more earnestly and intensively,” said Professor Dr. Orathai Chavalparit, Head of the Chula Race to Zero Working Group on Policy and Planning, and lecturer from the Department of Environmental Engineering, Faculty of Engineering, Chulalongkorn University.

As a citizen of the country and the world, Chula recognizes its responsibility to the public and to take this issue seriously and to be in line with the Sustainable Development Goals (SDGs), one of Chula’s strategies for 2021-2024. The President of Chulalongkorn University, therefore, announced the pledge to reduce greenhouse gases on campus last September with two main goals as follows:

1. “Carbon Neutrality by 2040”

2. “Net Zero Greenhouse Gas Emission by 2050”

To reach its Net Zero goal, Chula needs cooperation from everyone in the Chula community and plans are needed to reduce energy consumption in both the short and long terms. Chula has designed a five-strategy Chula ’2050 Net-Zero Transition’ plan as follows:

1. Energy Transition​
Chulalongkorn University has replaced its existing energy system with a Solar-PV development — a Zero-Carbon Energy System.

“Chulalongkorn University campus is in an urban area, so space is limited, and solar energy is most suitable for the university.”

Chula has signed an agreement with the Metropolitan Electricity Authority (MEA) for a pilot project to install rooftop solar panels for 65 buildings across the campus. Currently, installation has been completed in 14 buildings, and installation in the remaining buildings is expected to be completed by the end of 2023.

“If (the panels) are installed and used in all buildings, Chula will replace 25% of the university’s electricity consumption.”

In addition, Chula will concentrate on appropriate green building designs for new constructions, such as the layout and direction of the buildings to correlate with sunlight, while emphasizing the use of natural light to reduce the use of electricity.​

2. Improving Energy System Resilience
Chula has conducted a lifetime inspection and evaluated the efficiency of electrical equipment to convert them to energy-efficient ones in common buildings such as light bulbs and air conditioners. In addition, there are improvements in indoor air conditioning systems by installing heat monitors, ventilation, and cooling systems, as well as the Building Energy Management (CU BEMs) in buildings throughout campus to effectively and efficiently monitor and control energy consumption in each building through applications and dashboards. These systems which can report peak load periods and release of carbon dioxide (CO2) is designed by the Smart Grid Research Unit (SGRU), Department of Electrical Engineering, Faculty of Engineering in collaboration with Tokyo University and the domestic and international industrial sector with funding support from the Energy Conservation Promotion Fund (ENCON Fund), Ministry of Energy.

3. Creating Green Growth
Chula has supported national and international research and cooperation including green investment to develop carbon-free technology. The Bio-Circular-Green Economy Technology & Engineering Center, Faculty of Engineering, Chulalongkorn University, has collaborated with the government sector, private sector, industrial sector, and public organizations under the name Thailand CCUS Consortium aiming at planning, research, and development of carbon capture, utilization, and storage (CCUS) technology. This is an important step in the repurposing of CO2 that was originally seen as pollution, for value-added commercial uses and elimination of pollution for the environment.

In addition, Chula researchers have successfully converted carbon dioxide into methanol using less energy and giving high yield as part of a research project Carbon Dioxide (CO2) Conversion to Higher-Valued Products with the support of the Research Cess Fund (RCF) of the Malaysia-Thai Joint Authority (MTJA).

In 2022, 2565, Chula has been focusing more on energy transition and clean energy. Chula Faculty of Engineering has signed an agreement with Hitachi Energy to promote and support the education, research, development, and technological learning on energy-related topics such as carbon neutrality, microgrid, micro electricity generation, and management system for communities using mainly renewable energy, Battery Energy Storage System (BESS), electric mobility (e-Mobility), green hydrogen, as well as studying sustainable energy future.

4. Lifestyle Transition
Chula has also campaigned for students and personnel to use public buses within the campus with choices of low-carbon transportation such as electric buses, bicycles, electric tuk-tuks, and electric scooters. Covered walkways have also been installed to connect various buildings within the University to facilitate the commute of the Chula community.

Chula has also implemented the Chula Zero Waste Project on campus and surrounding communities to strive for zero waste from the source to the destination and reduce the amount of waste to landfill using the 3Rs rules, including Reduce, Reuse, and Recycle. Participation from the Chula community, including students, personnel, and vendors on campus has also been encouraged through awareness building so that everyone pays attention to their environmental impacts, and the waste generated in their daily life on campus, as well as changing their behavior to a more sustainable lifestyle for a sustainable environment.

Earnest implementation during the first five years of the project helped reduce waste by about 40 percent which is more than the original target of 30 percent and demonstrated the potential for management to drive cognitive-behavioral change in waste management. The project also set a goal to reuse 75 percent of waste by 2040.

Moreover, Chula encourages personnel and students to carry personal glasses or water bottles to reduce the use of single-use plastic cups, while preparing drinking water dispensers, and campaigning for stores in the cafeterias to substitute biodegradable Zero waste containers for single-use plastic bags. In the future, Chula plans to support a low-carbon diet to reduce meat consumption and promote the consumption of low-carbon plant-based foods such as vegetables, fruits, grains, or protein from legumes, as well as reducing the consumption of processed foods, and the use of single-use plastic food packaging.​ These measures require cooperation from cafeteria vendors on campus.

5. The Social Transition Social Support System

To encourage the Chula community to be part of the greenhouse gas reduction drive within the campus, there are plans to organize activities and projects such as discussion forums, short clip contests, and exchanges of information between students and personnel through online media channels. This is to raise the awareness of the Chula community on the importance and consequences of climate change that would lead to behavioral change and new conscience to prepare for a sustainable low-carbon society.​

“Although the management system to reduce greenhouse gas emissions that Chula has adopted is a system that has been used abroad, many systems are not yet widespread in Thailand. Therefore, Chula would like to be one of the leaders of change and a model of educational institutions that pilot the development of green research and innovation that can reduce carbon dioxide emissions in a real and sustainable way. We believe that we can and will expand to other institutions or agencies in Thailand to work together towards a sustainable low-carbon society.” Professor Dr. Orathai concluded.

Investigating geopolymer ceramic: Pioneering IMAT research in Oxford

Universiti Malaysia Perlis (UniMAP) has become the first university to conduct research using Imaging and Materials Science and Engineering (IMAT) at the STFC Rutherford Appleton Laboratory in Oxford, owned by the Science and Technology Facilities Council under UK Research and Innovation (UKRI), to study the materials used in electric vehicles.

This is in line with Malaysia’s aspiration to reduce greenhouse gas emissions, with transportation being one of the six main sectors as stated in the Green Technology Master Plan 2017-2030.

Principal Investigator, Associate Professor Dr. Mohd Arif Anuar Mohd Salleh, said that IMAT research is used to focus on weak links in electronics used in electric vehicles. He added that the collaboration with Professor Dr. Mohd Mustafa Al Bakri Abdullah, researcher from the Faculty of Chemical Engineering & Technology, UniMAP has resulted in the production of composite materials by incorporating geopolymer ceramic as reinforcements in soldering materials.

Two HKBU distinguished scientists elected members of Academia Europaea

Two distinguished scientists at Hong Kong Baptist University (HKBU), Professor Jia Wei, Cheung On Tak Endowed Professor in Chinese Medicine and Associate Dean (International Collaboration) of the School of Chinese Medicine, and Professor Cai Zongwei, Kwok Yat Wai Endowed Chair in Environmental and Biological Analysis and Director of the State Key Laboratory of Environmental and Biological Analysis, have been elected as a Member and a Foreign Member of the Academia Europaea respectively this year.

This prestigious recognition underscores Professor Jia’s exceptional contributions to the field of metabolism and physiology, and Professor Cai’s remarkable achievements in environmental and analytical chemistry.

Established in 1988, the Academia Europaea is the pan-European Academy of Sciences, Humanities and Letters. It is committed to advancing and disseminating excellence in scholarship across a wide range of disciplines, including the humanities, law, economic, social, and political sciences, mathematics, medicine, and all branches of the natural and technological sciences. It comprises around 5,000 distinguished scientists and scholars, including 83 Nobel Prize laureates.

Professor Jia is a renowned scientist in metabolomics and has a distinguished career in the pharmaceutical and medical field. Since joining HKBU in 2019, Professor Jia’s research has primarily focused on the identification of biomarkers in various metabolic diseases and investigating the mechanisms of key metabolic pathways involved in disease pathogenesis.

Currently, Professor Jia serves as the Director of the Hong Kong Traditional Chinese Medicine Phenome Research Centre, the first phenome centre focusing on Chinese medicine in both local and global contexts. Under his leadership, the Centre has attracted top global talents to conduct high-quality molecular and population-level translational research.

Professor Jia’s exceptional impact is demonstrated by a Google Scholar citation count of over 35,000 and a Google H-Index of 88. He was selected as one of the Most Cited Chinese Researchers in 2020, 2021, and 2022 by ELSEVIER, a leading global academic publisher. He has published 10 books, secured over 20 patents, and produced more than 500 papers in high-impact academic journals. Many of the papers published during his tenure at HKBU’s School of Chinese Medicine have ranked among the top 1% of most-cited journals in the field of biomedical sciences.

Professor Cai is a distinguished chemist in the field of environmental and analytical chemistry and an internationally acclaimed expert in environmental toxicology and human health research.

Professor Cai established and directed the Dioxin Analysis Laboratory since 2003 and the State Key Laboratory of Environmental and Biological Analysis since 2013, which have significant impact on environmental sciences and human health research in Hong Kong, the Great Bay Area and Mainland China. He was invited as the principal author for the Asia-Pacific regional reports on persistent organic pollutants under the Stockholm Convention by the United Nation Environmental Program.

Professor Cai has an outstanding research record with more than 700 scientific publications, 21,000 citations and a Scopus H-index of 73. He has been consecutively listed as the world’s most highly cited researcher in Stanford University’s list of World’s Top 2% Scientists in Analytical and Environmental Sciences. He is a Fellow of the Royal Society of Chemistry, and won the 2011 Second-Class State Natural Science Award for a collaborative research project. In 2018, he won the Higher Education Outstanding Scientific Research Output Award (Science and Technology) in Natural Sciences by the National Ministry of Education and the Award for Outstanding Contribution to Eliminate Persistent Organic Pollutants by the Chinese Society for Environmental Sciences. He also received the Distinguished Young Scholar Award in 2003 by the National Natural Science Foundation of China and was appointed as “Changjiang Scholar – Chair Professor” by the National Ministry of Education in 2013.

Midgut Gland of Scallops: A Valuable Source of Fucosylated Heparan Sulfate

Researchers show that fucosylated heparan sulfate, a branched acidic glycosaminoglycan, exhibits anticoagulating and neurite outgrowth-promoting activities

Marine invertebrates, including bivalve mollusks like scallops, are potential sources of heparin or highly sulfated glycosaminoglycans (GAGs) with biological activities. Exploring them further, researchers from Japan and USA recently investigated the GAGs derived from the midgut gland of the Japanese scallop. They found that fucosylated heparan sulfate (Fuc-HS) from the midgut gland has anticoagulating and neurite outgrowth-promoting activities.

Glycosaminoglycans (GAGs), including chondroitin sulfate (CS), heparan sulfate (HS), heparin, and hyaluronan are linear and acidic polysaccharides found in the extracellular matrix of all animal tissues. GAGs are widely used as functional ingredients in health products, pharmaceuticals, and cosmetics, and are prepared from biological samples such as shark cartilage and porcine intestinal mucosa. Consequently, the demand for new sources of GAGs is ever-present. For example, the supply source of the anticoagulant heparin—generally prepared from porcine intestinal mucosa in China—was threatened by African swine fever in 2018.

GAGs derived from marine invertebrates—animals without a bony skeleton—such as bivalve mollusks are highly sulfated or branched with neutral sugars. These modifications enhance their properties and enable them to perform various biological activities. In fact, heparin-like polysaccharides with anticoagulant activity were identified from some kinds of bivalve mollusks.

In this light, a group of researchers led by Dr. Kyohei Higashi, Associate Professor at the Faculty of Pharmaceutical Sciences at the Tokyo University of Science (TUS), has investigated the structure and biological activities of GAGs derived from the midgut gland of the Japanese scallop, Patinopecten yessoensis, a bivalve mollusk.

Their work, made available online on 25th March 2023, will be published in Volume 313 of the Carbohydrate Polymers journal on 1st August 2023. It is co-authored by Dr. Takeshi Wada and Dr. Kazuki Sato of the TUS and Dr. Shinji Miyata of the Tokyo University of Agriculture and Technology.

Dr. Higashi briefly discusses the motivation behind the present research. “Scallops are among the most popular marine ingredients in Japan. While their adductor muscle and mantle are edible, their midgut gland, a potential cadmium accumulator, is usually discarded as waste during food processing. However, it may be a promising abundant source of GAGs, whose structures remain unexplored.”

In this study, the researchers extracted crude GAGs from the midgut gland of the Japanese scallop, fractionated them by anion exchange chromatography, and analyzed their structures through high-performance liquid chromatography (HPLC), proton nuclear magnetic resonance (1H NMR), and gas chromatography–mass spectrometry (GC–MS) techniques. HPLC revealed that HS, which showed resistance to GAG-degrading enzymes such as chondroitinases and heparinases, is the major GAG present in the gland. However, its resistance to heparinases decreased upon mild acid hydrolysis, hinting at the presence of the fucosyl (Fuc) group. 1H NMR confirmed the same. It detected significant signals corresponding to the H-6 methyl proton of Fuc and small signals corresponding to H-2 or H-3 of glucuronate (GlcA) present in HS, showing that Fuc is attached to the C-3 position of GlcA. Furthermore, GC–MS detected peaks corresponding to 1, 3, 5-tri-O-acetyl-2, 4-di-O-methyl-L-fucitol and 1, 4, 5-tri-O-acetyl-2, 3-di-O-methyl-L-fucitol, enabling researchers to conclude that Fuc is 3-O- or 4-O-sulfated.

Lastly, the study highlights that Fuc-HS shows biological activities such as anticoagulation or blood clot prevention and neurite—a projection from the nerve cell—outgrowth promotion. “These findings indicate that the midgut gland of scallops is a valuable source of Fuc-HS with novel functions. A more detailed investigation of the structure and biological activities of Fuc-HS might reveal its other potential applications, similar to the fucosylated chondroitin sulfate (Fuc-CS) that shows antiviral, anti-diabetic, anti-tumor, and immunomodulatory effects,” points out Dr. Higashi.

The researchers expect the present study to help facilitate the comprehensive analysis of the structure and functions of naturally occurring and biologically active GAGs derived from unutilized sources, which may provide hints for developing glycoside drugs.

Here’s hoping for the discovery of more novel GAGs![vc_single_image image=”36351″ img_size=”full” alignment=”center”]

Future public health physicians learn about the health crisis of refugees in Malaysia

On 4th April 2023, 21 Master of Public Health (MPH) postgraduate students from Universiti Teknologi MARA (UiTM) Medical Faculty had the privilege of visiting the United Nations High Commission for Refugees (UNHCR) Malaysia, located in the heart of Kuala Lumpur.

As prospective public health physicians, it was a good opportunity to understand the role of UNHCR in dealing with the forgotten and forsaken health issues among migrant populations and their health-related challenges. Yet, our host, Mr. Jason Yeo, the assistant public health officer at UNHCR, posed a poignant question that would linger in our minds long after the visit ended.

“Imagine a scenario where your loved one falls ill, and you spend your last RM50 on a Grab car to rush them to a healthcare facility. However, upon arrival, you are told that treatment cannot be given for various reasons. How would you feel?” Mr. Jason proceeded to present a summary of health issues faced by the refugees, highlighting the stark differences between undocumented immigrants and refugees – undocumented immigrants still have the protection of their home countries and can return home, whereas refugees have no such privilege and cannot return home or risk persecution if they do.

He then shared staggering statistics with us, including the fact that there are approximately 100 million refugees worldwide and that Malaysia alone is housing 184,699 refugees and asylum seekers. Malaysia currently hosts refugees from over 60 countries, with the vast majority hailing from Myanmar. Unfortunately, more than a quarter of the refugees are children and people with medical needs. Malaysia has no refugee camps; hence, their presence can sometimes go unnoticed. Most reside in the slums or low-cost flats in metropolitan regions, with the highest concentrations in Kuala Lumpur and Penang.

Despite the availability of healthcare facilities, affordability remains a significant barrier to healthcare among refugees and asylum seekers in this country. The cost of living, along with the absence of prospects for official employment and lack of educational opportunities, exacerbate the difficulty in obtaining healthcare. It is evident that these displaced individuals were vulnerable to a wide range of health issues, many of which stem from urban poverty, including malnutrition, infectious diseases, and non-communicable diseases like hypertension, diabetes, and mental illnesses. Refugees in Malaysia have demonstrated remarkable resourcefulness by establishing their own support systems.

This includes helping one another to sustain their families, yet many still struggle to get needed services despite the initiatives and discounted healthcare fees. It is imperative that we address the root causes of these challenges, such as restricted employment and education opportunities to improve refugee health and well-being. Employment and education are important determinants of health, but refugees can neither work nor go to school legally.

A reliable income would improve their chances of getting proper healthcare. Education is key to securing employment to earn a living, allowing them to live healthier, consume better food and receive better quality healthcare. As we reflect on the situation of refugees in Malaysia, we must consider how we can best support them. This includes finding ways to enhance access to healthcare while also addressing the underlying social determinants of health that impact the lives of refugees. Through collaborative efforts, we can work towards creating a more equitable and just society for all.

UNAIR’s innovative products at ASEAN TISC Regional Meeting

The Directorate General of Intellectual Property (DJKI) Ministry of Law and Human Rights of the Republic of Indonesia (KEMENKUMHAM RI), in collaboration with the World Intellectual Property Organization (WIPO) and the Japan Patent Office (JPO) held the TISC ASEAN Regional Meeting. The event held at Amerta Hall, 4th Floor, MERR-C Campus Management Office, Airlangga University (UNAIR) on Tuesday, March 28, 2023, was attended by WIPO representatives and 24 delegates from all countries in the ASEAN region.

The meeting was themed: Best Practices in Technology and Innovation Support from a Local TISC Host Institution, which was presented by Prof. Dr. Mas Rahmah SH MH LLM. She is a Professor of Intellectual Property Law at the Faculty of Law (FH) UNAIR and Coordinator of the UNAIR Start-up Business Development and Incubation Board (BPBRIN).

The event was opened with remarks by the Director General of Intellectual Property (DJKI) KEMENKUMHAM Sri Lastami, and Mr. Alejandro Roca-Compana as Senior Director of the IP for Innovators Department (IPID), IP, and Innovation. Vice Rector for Research, Innovation and Community Development (RICD) UNAIR Prof. Dr. Ni Nyoman Tri Puspaningsih MSi was also attending.

In the forum, Prof. Mas Rahmah delivered a presentation on Practices in Technology and Innovation Support UNAIR. In her presentation, UNAIR has achieved many achievements, including in the field of development and research, which cannot be separated from the role of TISC.

“We have more than 400 research and innovation partners involved in 12 innovation consortium memberships. We also have seven innovation centers, and UNAIR innovators have been recognized as the world’s top 100 innovators or researchers. Of course, all these achievements are supported by the Technology and Innovation Support Center (TICS) role,” said UNAIR BPBRIN Coordinator.

Furthermore, Prof. Mas Rahmah explained TISC services as a local-based high-quality information technology access center. TISC is here to accompany and assist innovators in guiding the research journey until it becomes a product that will be distributed to the industry to be managed optimally.

“At UNAIR, we have technology and innovation support that provides services regarding access to high-quality local-based information technology to help them (innovators) create, protect and manage their Intellectual Property Rights (IPR),” she emphasized.

UNAIR has launched several products, including Merah Putih Vaccine, which is licensed by PT Biotis, Excelzyme, a product to prevent allergy triggers developed by PT Petrosida, Dentolaser, a digital product for teeth and gum care produced by PT Sarandi, Allergenic Extract is a product similar to Excelzyme developed by PT Biofarma, as well as the development of KHT Capsules or capsule shells made of seaweed.

Not only releasing products in the field of medicines and antiseptics, UNAIR also created other health products such as Fordontis Koniderm, a skin-lightening cream shaded by PT Konimex, Meditea, a herbal product that has been released and labeled by PT Asimas, Men Birth Control Pills, a product released in collaboration with PT Javaplant, Glucosamine, a food supplement product and Metabolite Stem Cell beauty product which is developed by PT Phapros. (*)

HKBU-led team discovers new box jellyfish species in Mai Po Hong Kong

A Hong Kong Baptist University (HKBU)-led team has discovered a new species of box jellyfish in the Mai Po Nature Reserve in Hong Kong. The new jellyfish species, which belongs to the family Tripedaliidae, was named Tripedalia maipoensis by the research team. It is the first discovery of a new box jellyfish species from the waters of China. The discovery also adds a fourth species to the Tripedaliidae family.

A paper describing the new species has been published in the international academic journal Zoological Studies.

Box jellyfish named after Mai Po

The research team was led by Professor Qiu Jianwen, a Professor of the Department of Biology
at HKBU. With collaborators from WWF-Hong Kong, Ocean Park Hong Kong and the University of Manchester, the team collected the jellyfish samples from a brackish shrimp pond, locally
called “gei wai”, in the Mai Po Nature Reserve during the summers of 2020 to 2022, and they found that the samples contained a new species.

Professor Qiu said: “We named the new species Tripedalia maipoensis to reflect its type locality – where the new species was first found. Although it is currently known only in Mai Po, we believe that this species is also distributed in the adjacent waters of the Pearl River Estuary as the gei wais are connected to the estuary through a tidal channel.”

Fourth species of the family Tripedaliidae  

Named for its cube-shaped body, the box jellyfish, (or scientifically known as class Cubozoa) belong to the phylum Cnidaria. Even though the class Cubozoa is one of the smaller groups among the cnidarians, it includes some of the highly venomous marine animals that are widely known in the tropical waters.

The newly discovered Tripedalia maipoensis belongs to the family Tripedaliidae. It is the fourth described species of Tripedaliidae, and the third described species of the genus Tripedalia around the world. It has a transparent and colourless body with an average length of 1.5 cm. There
are three tentacles that are up to 10 cm long at each of its four corners. Pedalia, a flat pedal-shaped structure at the base of each tentacle that looks like a boat paddle, allows box jellyfish to produce strong thrusts when they contract their bodies. They can thus swim faster than other kinds of jellyfish.

The box jellyfish with 24 eyes

Like other box jellyfish, Tripedalia maipoensis has 24 eyes. The 24 eyes are equally divided into four groups, and each group of six eyes is located inside a sensory depression called a rhopalium on each side of the bell. In each group of eyes, the researchers believe that two of them have lenses that enable image-forming, while the other four can only sense light.

Box jellyfish are also characterised by having a velarium, a membranous and muscular sheet that constricts the opening of the bell. There are canals in the velarium which run along the bell margins and allow water to enter the bell. In the new species, the velarial canals are biforked into multi-branches, which distinguishes them from other species of the same genus.

First discovery of new box jellyfish species in Chinese waters

The research team compared samples of Tripedalia maipoensis with those of other closely related species using morphological and molecular methods.

It was discovered that the new species exhibits greater diversity compared to Tripedalia cystophora – its closely related species that have been widely reported in the tropics and subtropics including Jamaica, Florida, Singapore, Australia, and India.

Professor Qiu said: “Box jellyfish are a small group of cnidarians with only 49 species reported worldwide. They are poorly known in Chinese marine waters. Our discovery of Tripedalia maipoensis in Mai Po – a relatively well-studied area in Hong Kong – highlights the rich diversity of marine life in Hong Kong and even the whole of China.”

Please click here for photos of the jellyfish and a video on its discovery.