TPU-developed drug tested in Mexico to protect healthcare providers from COVID-19

An international research team, including the chemists from Tomsk Polytechnic University, proposed using a product based on silver nanoparticles to protect healthcare providers from COVID-19. It was successfully tested at the General Tijuana Hospital in Mexico. A total of 232 physicians and healthcare workers at the hospital who interacted with patients with the coronavirus disease took part in the voluntary trials. Only 1.8% of those who used the product fell ill or had a mild illness. Among those who did not use it, the illness rate was 28.2%. The research findings were published in PLOS ONE (IF: 3.24; Q1). The pharmaceutical product has also underwent a series of additional tests in an accredited laboratory in Spain.

Our international team includes both the university researchers from Tomsk Polytechnic University, the National Autonomous University of Mexico (UNAM) and a number of other institutes in Mexico and Spain as well as the developers from the research and production private companies Vector-Vita (Novosibirsk) and Bionag (Mexico). We have been researching into the preparations based on silver nanoparticles for the past 20 years, and extensively advancing them both in Russia and abroad. We have developed a basic drug called Argovit, and launched its production in Novosibirsk,” says Alexey Pestryakov, professor at the Research School of Chemistry & Applied Biomedical Sciences of Tomsk Polytechnic University.

The developed drug is a concentrate containing silver clusters (nanoparticles) no larger than 35 nanometers in size, surrounded by a polymer shell made of polyvinylpyrrolidone or gelatin. It can be diluted and used to create gels, ointments, sprays and liquid medications.

“We hold a whole set of patents for the formula itself, the technology, and its use to treat a number of diseases. It so happens that our team has close ties with the Mexican scientific and medical community. Therefore, a number of studies are being conducted there. In this country, a drug based on Argovit is successfully used, for example, to prevent and treat a diabetic foot syndrome and a number of other human and farm animal diseases (cow mastitis, canine distemper, shrimp white spot syndrome, etc.). In Russia, there is a form of the drug certified as a prophylactic remedy for oral cavity treatment. Since the drug has already shown its high effectiveness against bacteria and viruses, with the start of the COVID-19 pandemic, we assumed that it could be effective for this purpose as well,” explains the professor.

The Tijuana study was conducted over nine weeks in the spring of 2020. It involved two groups of healthcare workers. In the first one, 114 employees gargled their nose and throat twice a day with a solution containing silver nanoparticles. The second group of 117 people did not do it. Both groups used regular personal protective equipment for a covid hospital – masks, protective suits, etc.

“As a result, only two cases of infection were confirmed in the first group; those who fell ill had a mild form of the disease. In the control group, which included the healthcare staff of the hospital who did not use the Argovita solution, 33 employees out of 117 fell ill with COVID-19, i.e. 28.2%,”

says Alexey Pestryakov. In order to publish the research findings in the journal, we conducted a number of additional in vitro studies in Spain. Unfortunately, it took almost a year to publish the results. This is the reality that all drug researchers face, despite the urgency of the issue”.

The agent used in the study falls into the category of colloidal silver preparations.

“Silver belongs to the class of heavy metals, hence as regards its use in medicine, it is rightly subject to stringent requirements for toxicity. The peculiarity of colloidal silver drugs is that their effectiveness and safety depend on many factors: the size of nanoparticles, their shape, the polymer shell used. The creator of each particular drug has to prove the efficacy and safety of the substance. We have gone all this way before. The substance itself and the drugs based on it have an extensive scientific evidence base for safety and efficacy. We have published over 80 scientific articles with the research results, obtained over 20 patents and patent applications. The research proves that in therapeutic doses the drug is not toxic,” the researcher says.

According to an expert, Mexico is now in the process of registering the drug for use as a prophylactic remedy against COVID-19.

“Our ultimate goal is to eventually use the drug in therapy and, of course, in our country. This summer, the medical institute of the North Caucasus State Academy in the city of Cherkessk conducted a study of the drug with the voluntary participation of 92 patients with COVID-19 in mild and moderate forms.

They were all treated with a standard therapy for this disease, however the inhalations with our drug twice a day were additionally included in the treatment regimen. The obtained results proved the increase of therapy efficiency when including nanosilver drug in the complex treatment regimen for COVID-19, at least for its mild and non-neglected forms of the disease. The treatment periods were shortened by an average of four days,” adds Alexey Pestryakov.

For more details about the research findings, please, refer to the article published in the Siberian Scientific Medical Journal.

Natural History Museum of Nan receives honorable mention

Chula’s Natural History Museum of Nan has received the honorable mention award under the concept “Reimage, Relearn, and Reinvent during in the COVID-19 pandemic”.

The Natural History Museum of Nan features exhibits related to the life and culture of the tribes of Nan and is home to a number of priceless local antiques. It was designed to foster the love and pride for Nan’s natural resources, arts, culture, and local wisdom, raising awareness for the need for conservation and environmental protection, and building knowledge on local ecology and sustainable use that supports biodiversity. The museum houses 10 exhibition rooms that contain specimens of plants, animals, and various biological, physical, and cultural resources in Nan province.

Watch a video clip of the Natural History Museum of Nan at https://youtu.be/_yOAS0DfZ9o

The Natural History Museum of Nan location:

2nd floor of Wichakham 2 Building, Pha Singh Research and Technology Transfer Station, Center for Learning and Academic Services, the Network of Chulalongkorn University, Nan Province.

Looking for the Earth’s twin

What is a hot Jupiter? How can an Earth-like planet be discovered? How can it help us learn more about our planetary system? Roman Baluev, Candidate of Physics and Mathematics, Senior Research Associate in the Department of Astronomy at St Petersburg University, answers these and other questions about modern astronomy.

Mr Baluev, could you please explain what exoplanets are? What are they like?

Exoplanets are planets that orbit around stars other than the Sun, i.e. outside the solar system. Among the first planets to be discovered since 1995 were the so-called hot Jupiters.

Scientists have discovered a whole class of celestial bodies that are similar in mass to our Jupiter, but are much closer to their star, at a distance of less than 0.1 astronomical unit. As a result of such a short distance, their atmospheres are heated to enormous temperatures of about 1,000 K. The Solar system has no such planets.

An astronomical unit is a traditional unit of measurement in astronomy that amounts to the average distance from the Earth to the Sun. For example, the distance from Mercury (the closest planet to the Sun) to the Sun is about 0.3-0.4 astronomical units.

At first, it seemed to be the dominant class of extrasolar planets as other types were very rarely found. It can be explained by the fact that hot Jupiters were much easier to detect given the accuracy of the measuring instruments that existed at the time. Later on, however, from the year 2000 or so, when the equipment became more advanced, more distant planets, including those similar to our Jupiter, have been discovered. It became clear that the class of hot Jupiters is not that numerous.

Moreover, among the extrasolar planets, there were also discovered hot earths, which are located very close to their stars. As a result of the high temperatures, there is no life on them, nor can there be any. There are also hot Neptunes (or hot super-Earths).

Why are scientists searching for new planets? What does it help to understand?

For a long time, researchers have built theories about the formation of planetary systems and based them only on the data from the solar system. However, planet Earth is quite special – we and other living organisms emerged here. Apparently, this is a rare occurrence in the Universe: we know of no other such examples. One could study our planetary system in detail down to its chemical composition and the origins, but this would not answer the question of whether it is unique or whether it is a universal standard?

The first discoveries of exoplanets provided additional statistics which were enough to develop a new theory of planet formation. Hot Jupiters, for example, shattered existing beliefs, as their origin cannot be explained by the old theories. Our planetary system has only one Jupiter at a distance of about five astronomical units from the Sun, and it has a substantial mass. The inner region of the solar system has only small planets: Mercury, Venus, the Earth and Mars. The first exoplanets that have been discovered have a mass comparable to that of Jupiter. However, they are 20 times closer to their star than the Earth is to the Sun. Their origins are unclear: located so close to a star, they simply could not have had the material to form a planet of such mass.

Scientists have therefore developed a theory of planetary migration. It suggests that a planet is formed far away from the star but, through interaction with the protoplanetary disk, it gradually moves closer to the star and migrates towards the central regions. We can detect the planet now by observing the scattering of material from the protoplanetary disk.

A protoplanetary disk, or proplyd, is a disk of dense gas, which subsequently forms planets, that rotates around a young star.

This raises the question of why our Jupiter has not migrated. It can be down to the parameters of the protoplanetary disk: the amount of matter that was initially there; its viscosity; and its chemical composition. There is a whole field of research in mathematics, hydrodynamics, and even magnetic hydrodynamics to explain this.

There has also been further development of the theory of gravitational instability in the protoplanetary disk, which has explained the presence of such planets in the central regions around the star without migration. The discovery of exoplanets gave a good impetus to this research and formed an entire branch of astronomy.

What can astronomers learn about exoplanets staying so far away from them on Earth?

The planets that revolve close to the star are so hot that they emit their own light in the infrared band and this light can be detected as they drift behind the star’s disk. As the planet emerges from behind the disk, it slightly contaminates the star’s light. If we look at the spectrum, we see that the planet adds its own lines which can be registered and interpreted.

This is how we get information about the general composition of the planet’s atmosphere. This is useful as since we know the chemical composition of the gas giants in the solar system, we can tell the differences in the chemical composition of exoplanets. This has become a branch of science in itself.

Another field involves the study of the atmospheric dynamics of planets. When a planet passes behind the disk of a star, this effect can be recorded and the asymmetry of this phenomenon in the infrared region of the spectrum can also be measured. This provides information about the scattered light surface brightness distribution of the visible disc of the planet. After all, the star heats the planet unevenly – the atmosphere is always hotter in the centre (at the equator). Moreover, the planet rotates and, due to various hydrodynamic effects, there are strong winds. The hot spot may shift and take some non-trivial forms. This is how we can get information about the hydrodynamics and thermal profile of the planet.

As there are many types of exoplanets, they become a kind of experimental cauldron, an experimental laboratory created by nature.

What methods are used to detect planets?

There are several ways of detecting extrasolar planets. One of the principal methods is the radial velocity method, or Doppler spectroscopy. Earth-based telescopes enable us to observe the star ‘wobble’ as a result of gravitational disturbance from the planet. What we can see is not even the ‘wobble’ itself but variations in the star’s radial velocity. It is the speed at which the object moves away and towards the observer, which can be measured by spectroscopy. In other words, we find an exoplanet by the change in the subtle characteristics of the star’s light, or, more precisely, by the periodic shift of spectral lines due to the Doppler effect.

The Doppler effect, named after the Austrian physicist Christian Doppler, explains the change in frequency and length of waves caused by the movement of their source and receiver in space.

There is also the astrometric method, when scientists measure the direct oscillation of a star around the centre of mass of the planet, rather than the spectral parameters of the star’s luminescence. This is a rather exotic method because such an effect is very difficult to capture. It was for this kind of measurement that the Gaia astrometric spacecraft was launched in 2013. It has been flying for some time now and may be able to discover many new planets in the future. However, the data it has collected so far is insufficient as such precise measurements require the full amount of information from the entire expedition, and it still needs to be processed by special algorithms.

Another method is microlensing, which makes it possible to discover planets orbiting very distant stars. From the Earth, clusters of such distant and dull stars merge to form the Milky Way. Sometimes two unrelated stars can be at different distances from the Earth but happen to align in the same line of sight for us. At this point, the closer star will use its gravity to focus the light of the background star onto the observer. At this point, the background star will have brightened for a period ranging from a few hours to several days. If there are planets rotating around the nearest lensing star, each of them will also play the role of a small lens. On the light curve, we will see the anomalies caused by these planets.

Everything has to be right: the stars should align on the same line; and the plane of the planets’ orbits and the planets themselves should take the right position. This is a very rare and unlikely event. This method, nevertheless, was popular at the time of the OGLE project on microlensing, during which there was discovered a considerable number of planets in our galaxy. However, this method had an important drawback as microlensing happens only once for each object.

The OGLE (Optical Gravitational Lensing Experiment) is a Polish-American project to study dark matter using the method of gravitational microlensing.
One of the current methods of detecting exoplanets, which competes with the radial velocity method, is the transit method. It uses photometry and is primarily aimed at the planets orbiting close to the star. At such a distance, the planet’s plane of rotation is likely to pass through the Earth and we will periodically see the celestial body projected onto the star’s disk. The planet in this case remains invisible to us, but we do observe that it slightly dims the star’s light by about 1% in recurring periods. To spot this, we need precise photometry, which is simpler than the radial velocity method. The Doppler method requires special highprecision spectrographs. In the case of the transit method, such precision is not required.

The transit method, however, has another drawback: the planet’s orbit has to be oriented towards the Earth for the transits to occur periodically. If its orbit is flat, the transit will not be detected. The probability of such a plane orientation is quite low. If a planet is as far away from a star as the Earth is from the Sun, the probability of detecting it is very small. It increases if the planet orbits close to the star, but is still low.

What method do you use in your research?

The transit method has a spin-off, namely the transit-timing variation. Suppose there is a planet orbiting a star, and due to a certain plane of its orbit it periodically passes in front of the disk of that star. If there is one planet, the transit repeats with the planet’s orbital period.

However, if there is another planet that remains invisible, it will gravitationally affect the first planet and perturb its motion, thus disturbing the strict periodicity. So, one transit event will be a little delayed or ahead of the projected moment. Such deviations might suggest that there is another object in the system. Celestial mechanics can tell us a lot about an object and even help to calculate and construct its orbit.

Such deviations in timing can also occur because of the tidal interaction of the planet with the star. Over time, a planet loses energy and spirals slowly towards the star due to the small distance between them. The tidal force causes them to affect each other in the same way that the Moon causes the Earth’s tides. The planet is flattened and this deformation causes a continuous change of direction so the planet always faces the star with one side. Due to this effect, there is a loss of energy in the planet’s core. This means that the orbital velocity of the celestial body gradually increases. According to Kepler’s law, the closer an object to the star is, the faster its companion should move. It is a microscopic effect: in the case of the Earth, for example, the accumulated deviation in timing turns out to be only about a couple of minutes over a 10-year observation period.

There are two such planets known today: WASP-12 and WASP-4. The latter is being observed in South America by amateur astronomers at our request as part of the EXPANSION project, which I will talk about a little later. The study was carried out in parallel with another international team and they happened to publish the results first as they had observed the accelerating moments of the transits. We were more cautious and noted some complications in interpreting the data.

The observed effect could have been the result of systematic errors, in particular the impact of stellar spots. If a star has homogeneous brightness over its entire disk, the transit will look beautifully smooth, just like in the textbook. Stars, however, almost always have spots and it may happen that a planet will take a ‘splash’ over the top of this spot during its passage. Then the photometric curve would show an anomaly, which would distort the result. In the end, we did confirm the timing acceleration effect, but the amplitude of the systematic acceleration was half what the second scientific team had claimed.

How do astronomers acquire data on exoplanets?

A colleague of mine, Evgenii Sokov, has organised an international network of telescopes among amateur astronomers, which also includes professional observatories. The network is made up of several dozen telescopes that conduct regular observations of the transits of various exoplanets across the sky. There are now just over 20 such planets, and WASP-4 was one of them. These planets have long been known and described, and we continue to accumulate data on their timings, thanks to the project.

This project sprang from the Czech Exoplanet Transit Database. For some time, observations of varying quality have been accumulated in this database, but most of them are not of very high quality as they were taken by amateurs. Such data should be carefully selected and include only the objects whose data quality is more or less adequate. On the basis of this database Evgenii Sokov has founded the EXPANSION project and brought together people who are willing to conduct observations of exoplanets on a regular basis.

We also cooperate with the Special Astrophysical Observatory of the Russian Academy of Sciences. They have recently commissioned a new spectrograph with the level of precision that enables observations via the radial velocity method.

Is there any chance of finding an Earth twin?

Astronomers around the world would certainly wish to discover such a planet. This is the cutting edge of exoplanet research and the most intensive studies are being conducted in this field. However, the task is not easy: you need to find a planet with the same mass and at the same distance from the star as the Earth. There is no point in finding a white-hot Earth where no life can exist.

A full twin to the Earth has not yet been found. However, similar planets have been discovered near low-mass red dwarfs. Due to their low mass, these stars are more sensitive to planetary disturbances, making it easier to discover lower-mass exoplanets near them. Red dwarfs also have a life zone closer to the star because they produce a fainter light than the Sun. Their exoplanets can orbit closer to the star without getting as hot as hot Jupiters.

The habitable zone or life zone is the area around a star with the most favourable conditions for Earth-like life.

Looking for a complete analogue of the Earth requires a high precision spectrograph with a radial velocity measurement accuracy of 10 centimetres per second. The best spectrograph available today only allows an accuracy of 30 centimetres per second. The search for twin Earths is therefore a great challenge for engineers in many ways. High precision instruments need ultra-high stability. To achieve this, they are installed in a special protective case that maintains constant pressure and temperature.

High precision instruments are not enough. It is important to remember about spots and other unstable phenomena, such as flares, granulation and so on, in the photosphere of a star. Roughly speaking, the surface of a star is turbulent and this causes additional noise and distortion in the measurable radiant velocity. As a physical object, a star’s radial velocity doesn’t change. However, the problem is that it is not measured directly – we use a spectrograph based on the Doppler effect. The spectra of a star reflect its unstable outer envelope. This instability varies by one metre per second.

In short, to minimise the natural astrophysical noise of a star, it is necessary to create special algorithms that will process and filter it. This is the only way to achieve the accuracy needed to discover an Earth-like planet. No matter how difficult it is, I think it will happen sooner or later.

Miracle of ‘Thai–pattern woven fabric’ when ‘wisdom’ reinterpreted

The beauty created by nature has been merged with the local cultural heritage of Thailand, initiating a powerful piece of work and full of stories that can be endlessly inherited.

The day the world was united, youth and the people of new generation project ideas to be connected to the world. “Thainess” is therefore interpreted in a different dimension, however maintain the essence and the foundation that transcends through time from era to era.

Similarly to the work “Chromatography”, a set of 33 shades of Thai pattern fabric, designed by “Fah”, Ms. Pemika Piahiang, a 4th year student from the Faculty of Fine and Applied Arts, Textile and Fashion Design Program of Thammasat University (TU) that has brought ‘tresure in the soil’, the existing asset of Thailand to be applied to modern way of thinking.

Until being able to win the “first prize” from the Cultural Textile Awards 2021 in the category of “Creative Textiles” under the project of developing cultural heritage of Thai fabrics to the world of the Department of Cultural Promotion, Ministry of Culture (DCP).

Fah said that Chromatography was a continuation of the thesis project from Thammasat University, a woven tweed fabric by raising the level of education to another level of detail in order to create fibers and design fabrics that are different, cutting-edge, starting from the fibers of each region that are considerably distinctive. For example, wool fibers from Mae Hong Son province, Eri silk fibers from Khon Kaen province, silk shell fibers from Phetchabun province, silk yarn and handmade cotton from Sisaket province.

The design concept of this woven fabric is from early experience in primary school that the teacher allowed her to conduct an experiment to separate colors by marking a point using black chemical pen, which there were red-blue-yellow colours spreading out. If studying art-based subjects, you would know that when these three colors are mixed together it will also become black.

This was the original idea of ​​dyeing the fibers black from natural dyes. Then, natural colors have been applied using color composition principles into the work, the woven fabric “chromatography” has approximately 33 color combinations.

For example, a pinkish brown color is obtained from coconut husk, red from shellac, blue from indigo, dark brown from the golden shower pods, yellowish-brown color from coffee grounds, yellow from garcinia barks, yellow from maclura cochinchinensis barks, and golden brown color from dried mangosteen peel, etc.

The award winner said that at first she wanted to study fashion as she wishs to design clothes, but in the first year, Thammasat University will teach the basics of both fashion and textiles. When learning, it was very enjoyable to make fibers, produce fabrics, which was even more fun than making patterns or fashion in general.

“It is as if you have to go back to the basics first, which is that, before making any clothes, we have to produce the fabric first. So, I feel like I love the steps that we started from the beginning. The important thing is the encouragement from the lecturers at the faculty, because every one of them cares about every student, therefore the more we enjoy what we learn,” said Ms. Pemika.

“In the future, I would continue to further develop bodies of work. I want everyone to see the importance as each piece of woven fabric has a value in itself. It depends on how further we can develop. Personally, I would like to develop my work to be more of an international level for people of all age to fall in love with this woven fabric or this particular pattern. I want them to feel that it is not outdated and can actually be used in daily life, and that I wish to have my own brand,” said Ms. Pemika.

For “Jimmy”, Ms. Supattra Klahaan, a student of the Faculty of Fine and Applied Arts from Thammasat, the author of the work “Efflorescence of Feminine” or the imaginary projection of a woman with a flower that is representing beauty, which won the Award Winner of the “Cotton” category from the contest under the same project, saying that the inspiration for the design was to be influenced by the colors from the Thai Textiles Book Spring/summer 2022.

For the distinctiveness of the work, it is fabric weaving with natural fibers from cotton, expressed through weaving with plexiglass pattern combined with ikat pattern technique. Vibrant color tones are used to represent purity, sweetness and beauty to create a new symbolic shape. The fibers are dyed from natural pigments such as blue from indigo, yellow from garcinia barks, pink from shellac and brown from golden shower pods.

“Knowledge gained from the classes is practical. Since the start of the working process on warp preparation, yarn reeling, patterning, natural dyeing techniques, weaving techniques, to communication methods, coordination, and most importantly, the design concept that has to take into account the user as a primary concern,” said Jimmy.

Ms. Supattra also said that she wants those who are interested or those with purchasing power to help support the work of villagers in all four regions of Thailand in order to create an even distribution of income. By buying one villagers’ product, you will receive an item that indicates the arts and culture of that area, while the villagers will gain income leading to the morale and motivation to create the next piece in order to continue inheriting and preserving the existence of the Thai fabric of the areas.

Virtual IBRO-APRC Associate School of Neuroscience UiTM 2021

The Faculty of Pharmacy and Research Management Centre, Universiti Teknologi MARA (UiTM), Malaysia, are proud to have organised and hosted the prestigious ‘Virtual IBRO-APRC Associate School of Neuroscience UiTM 2021’ for the third time from the 2nd until the 6th of August 2021 via the Webex Cisco online platform. The theme for this year was “Gut Microbiota and the Gut-Brain Connection: There is Science in Gut Feeling After All”. The Associate School of Neuroscience Programme, generously funded by the International Brain Research Organisation (IBRO), aimed to provide a holistic learning and research experience on the importance of gut microbiota and the Gut-Brain Axis for young aspiring neuroscientists from the Asia Pacific region.

The associate school, which covered three (3) subthemes: the influence of the Gut-Brain Axis on the CNS, in vivo models for the Gut-Brain Axis research, and the impact of lifestyle changes on the Gut-Brain Axis; provided both fundamental and translational knowledge on neurological disorders related researches to all participants. As one of the strategies to facilitate a holistic learning experience, each subtheme was accompanied by talks, short forums, skill development and workshops (Day 1-3). A mini-symposium was also held on Day 4 for participants to showcase their research outcomes. The symposium culminated with a wonderful sharing from the AGELESS Long Term Grant Scheme (LRGS) researchers and a theme talk presentation. Awards for best oral presenters were also presented to the IBRO-APRC associate schoolers at the end of the symposium. A virtual excursion was held on Day 5.

The associate school was also pleased to feature 22 speakers from local and abroad (i.e., Australia, Canada, Thailand and USA). Altogether, 32 applicants from India, Malaysia and Syria were shortlisted for this year’s associate school, out of which 30 of them registered for the event and 28 successfully completed the programme. The theme talks, which were also open for registration to participants from local and abroad, had also attracted more than 70 attendees on average.

Overall, the virtual IBRO-APRC Associate School of Neuroscience UiTM 2021 was a success. At least 70% of the associate schoolers strongly agreed that the training was relevant to them and the content of the talks/workshops met their expectations. More than 90% of the associate schoolers also strongly agreed to recommend the IBRO-APRC Associate School of Neuroscience to their colleagues.

How material for high-speed switchable devices transitions into conducting state

A team of physicists from Saint Petersburg Electrotechnical University “LETI” studied and described the main factors that affect the transition of vanadium dioxide (VO2) thin films into the conducting state. The team identified two different transition mechanisms that depend on the number of defects in a sample: the fewer defects, the less voltage is required for transition, and the more independent voltage threshold is from temperature. The results of the study were published in the Chaos, Solitons & Fractals journal.

In their normal state, vanadium dioxide (VO2) films cannot conduct electricity. However, when subject to a certain voltage level, their resistance reduces by up to a hundred thousand times. Such a transition can happen very fast — in less than a picosecond. The mechanism of this process is still largely unknown, but this unique property makes vanadium dioxide films a promising material for smart windows, thermal imagery sensors, and artificial neurons for next-generation computers.

“One potential area of application of VO2 thin films is active memristors. Thanks to resistive switching in active memristors, they can be used to simulate the behavior of voltage-gated ion channels in biological neurons, and phase transition in VO2 thin films makes it possible to model different types of spike activity of neurons. Potentially, the modeling results could help scientists study the time synchronization of the neurons that support the functional activity of the brain and find ways for their synchronization or modulation. Based on these studies, non-pharmacological correction methods for certain functional brain states could be developed,” says Natalia Andreeva, a lead researcher at the Nanotechnologies Science and Educational Center of ETU “LETI.”

In its work, the team from ETU LETI studied the switching dynamics in a broad temperature range: from -200 to +20°С. To do so, they made several identical samples by covering a sapphire base with a thin layer of vanadium dioxide using the method of reactive magnetron sputtering. During this process, particles are dislodged from a bar of the sputtered material by gas ions in a strong magnetic field. Then, different voltage levels were applied to the samples at different temperatures, and the team studied the current flows through VO2 thin films.

Based on the experiment results, the team divided all VO2 thin film samples into two types. The first one required more voltage to transition to the conducting state when the temperatures went down, and the second one did not exhibit any threshold voltage changes correlating with temperature. According to the team, the difference might be due to the number of defects, namely, ions of hydrogen and oxygen vacancies (i.e. areas lacking atoms of oxygen).

In some cases, the defects could act as electron traps, and for the transition to the conducting state to happen, all of them should be filled. This requires a certain threshold voltage. When a sample has a relatively small number of defects, the threshold voltage is low and does not depend on the temperature; the transition to the low resistance state in VO2 thin films is preferably electronically driven. On the contrary, at increasing the number of defects in a sample, the higher voltage bias is required for the transition to the low resistance state, and more likely that it is triggered due to thermal heating. In this case, the threshold voltage is temperature-dependent. When a sample is cooled down and subject to a voltage at the same time, more voltage is required for the transition with the temperature decreasing.

“We are going to continue working on this task in the framework of the state project “Bionic neuroarchitectonics.” Namely, we plan to model neuroprocessing activity using cutting-edge smart materials and technologies,” concluded Natalia Andreeva.

SPbU scholar on amending Criminal Code on abduction

According to official statistics, about 350 people are kidnapped in Russia every year. However, this number does not include the abduction of a child by relatives, because law enforcement authorities generally avoid initiating such criminal cases. Evgeniia Ivanova, a scholar from St Petersburg University, explains the cases when father and mother have the right to decide where and with whom a child lives, and when the law prohibits it.

In her dissertation ‘Abduction: Qualification and Liability’, Evgeniia Ivanova studied more than 1,300 cases of abduction and formulated recommendations on improving legislation in this area.

Ms Ivanova, why have you chosen abduction as the subject of your research?

There were a number of reasons. First and foremost, it was the wording of the Article, which is not ideal. The law provides only a name for the crime without defining it, so it is not very clear what the offender has to commit for it to be called abduction. Is it necessary to keep a kidnapped person in captivity for a long time or just a few hours? Is it necessary to have the abducted person removed somewhere, and does the distance matter? Is the motive and purpose of the abductor important? The law does not provide answers to these questions. Secondly, abduction is a crime that infringes on a person’s physical freedom. However, the law does not give us a clear definition of what freedom in general and physical freedom in particular is. Moreover, in reality not all people can exercise such freedom fully at their discretion. The insufficient research into these issues has piqued my interest and led to such research.

What kind of people do not have full control over their physical freedom?

There are three categories. First, there are those whose sentence involves the deprivation or restriction of physical liberty. Obviously, people held in correctional institutions are not free to move around. Secondly, there are people who have been appointed custody because of their incapacity. The place of residence of such people is determined by their guardians. Thirdly, there are children, who are underage.

Is this why you focus so much on the liability of parents and relatives for abducting children? Is it because the physical freedom of children is of specific nature?

Absolutely. It is also a pressing social issue. I think each of us has heard of scandals involving the kidnapping of children by their parents or other relatives. Foreign countries have the practice of prosecuting such people. However, Russian law enforcement agencies are reluctant to initiate criminal proceedings, citing that the Criminal Code does not stipulate such liability.

Is there no provision for it?

Parents are not liable because under the law (the Constitution and the Family Code) they are the ones who are responsible for where and with whom the child lives. The conflict between the parents over the removal of a child is therefore a matter of family law, not criminal law. The situation is quite the opposite if one of the parents is deprived of parental rights. If there are no parental rights, there is no right to determine the child’s place of residence. The person is legally a stranger to the child, so he/she becomes liable for kidnapping. The same applies to grandparents and other relatives of the child. They do not have the right to dispose of the physical freedom of the child, so they shall be held liable.

What if a child wants to live with a relative or a parent who has been deprived of parental rights? Should this be taken into account?

All things are considered, but only if the issue is resolved by legal means, whether it is a grandmother trying to get custody of a child or a parent trying to recover parental rights. Simply removing a child bypassing the legal procedure is a crime, and the opinion of a child, whatever age he or she may be, is legally irrelevant. However absurd it may seem, but a direct interpretation of the norms of the Constitution of the Russian Federation and the Family Code of the Russian Federation implies that for any minors the decision concerning their residence is made by parents. It is rather strange when a person aged sixteen can take care of their own medical matters, can get a job, can be held criminally liable, and at the same time is dependent on parents to determine the place of residence and spending leisure time.

What happens if living with parents endangers the life and health of a child, and a grandmother has to remove the child? Is it right to charge her with a criminal offence?

It is certainly wrong. That is why the Criminal Code of the Russian Federation provides for an exemption from liability for a person acting in cases of extreme necessity. If a child may be harmed and a person saves him or her, it is an act of extreme necessity.

Are there any changes that you could suggest to the Criminal Code that would allow improvement of the criminal legislation, in particular concerning the issue of criminal liability of child’s relatives?

My dissertation includes such proposals. However, it is a social problem and such problems cannot be solved solely by the norms of the most repressive branch of law, criminal law being the most repressive of all. It is necessary to develop comprehensive mechanisms that involve both family and civil law to ensure that the course of action of individuals in a given situation is clear.

The text of the dissertation and a video of the defence are available on the website of St Petersburg University.

Speaking about abduction in general, rather than just children, is it possible to solve the problem with legal instruments?

We can take measures to improve legislation and adopt acts at the level of the global community. However, crime is a social phenomenon, and in my opinion, the most effective way to reduce it is through social mechanisms.

Are there examples of countries where the problem of abduction has been, if not completely solved, then minimised?

Since 1 September 2016, St Petersburg University has been entitled to form its own dissertation councils to award the degrees of St Petersburg University.

In the course of my research, I have not come across a country that does not have provisions for abduction in its legislation. In my opinion, this shows that this offence is common to any state and is ‘normal’, insofar as one can speak of normality in relation to destructive behaviour. Of course, the specific nature of abduction varies from country to country. For example, in China, women are often kidnapped for the purpose of marriage, which is a result of the demographic situation (there are considerably more men than women in the country). The problem of abduction is unlikely to be completely solved.

Could you please tell us about the defence of your dissertation?

My defence was held in a mixed format: the members of the council who were in other countries and cities were present remotely. Of course, this was rather unconventional, but everything went well, largely thanks to my long experience of distance working at the University. The entire procedure took about 2.5 hours and I received a lot of very different questions from the members of the dissertation council. It was certainly an interesting experience.

Is the defence procedure under the rules of St Petersburg University difficult?

The defence does not seem very complicated. All the requirements for candidates are justified and the mechanism for submitting and verifying documents is well established. I personally had difficulties in selecting a foreign expert, but I admit that this is related to the topic of my research. What is unusual is the absence of opponents: the members of the dissertation council act as both evaluators and critics of the work. In my view, it is not therefore the candidate, but the members of the dissertation council who may find it most challenging.

What do you think of the requirement to publish the research in two languages?

Publication of research in a foreign language is necessary, in my point of view. This solves a number of problems in popularising the research abroad, since not every foreign specialist has a sufficient command of Russian to study scientific works.

What are your plans now, after the defence? Does a PhD degree open new doors for you?

Of course, having a PhD degree is very important. It will contribute to my teaching career at St Petersburg University.

Furthermore, I have already submitted a proposal to St Petersburg University Publishing House for the publication of my monograph. I would like to see it published this year. There are not many monographs on abduction, so my research might be useful.

 

New energy source for car is created in Al-Farabi Kazakh National University

Tolganay Temirgalieva, a doctoral student at Al-Farabi Kazakh National University, a researcher at the Institute of Combustion Problems, creates supercapacitors – new generation batteries. In the manufacture of lithium batteries, rare earth, reactive metals are used that are toxic during use and disposal.

The advantage of such batteries is a long life cycle: up to 1 million charge-discharges versus 3 thousand for lithium ones. In addition, supercapacitors are dozens of times lighter than traditional ones and release a charge very quickly: a mobile phone can be fully charged in just seconds.

Supercapacitors have less energy stored in 1 kg of the device than in a lithium battery. Energy capacity is increased due to nanotechnology. “Tolganai uses nanotubes instead of polymers used in lithium batteries. This is the uniqueness of her work, ”says Mukhtar Eleuov, a colleague of the inventor from the Institute of Combustion Problems.

The nanotubes were developed at Waseda University (Tokyo) under the guidance of Professor Suguru Noda. The Japanese have also created and are already selling carbon-based electrodes. But their material “Kurarai” has a capacity of 120 farads, and the materials of Tolganay – 180-200 farads per gram. Therefore, the Japanese professor began to cooperate with a scientist from Kazakhstan: from them – nanotubes, from us – coal from waste. “Using materials based on rice hulls and apricot kernels, it achieved good performance comparable to commercial activated carbon,” comments Professor Noda.

So far, the development of Tolganai can be used for electric vehicles. When the volumes of supercapacitors are “compressed” to the size of batteries for portable devices, the scope of their application will significantly expand.

EdUHK EdTech Innovations Claim 10 iCAN Awards

The Education University of Hong Kong (EdUHK) won 10 awards at the 6th International Invention Innovation Competition in Canada (iCAN), with three gold medals, one silver, one bronze and five special prizes, in August 2021.

With a commitment to creating a positive impact on learning and teaching, EdUHK scholars exhibited extensive expertise in scientific research and implementation of technology. These awards acknowledge the University’s solid reputation for research output and innovative technologies.

The five award-winning innovations cover different application areas, including language learning, life education and early childhood development. They are:

  1. VocabGO – An Augmented Reality English Vocabulary Learning App
    Principal investigator: Dr Song Yanjie, Associate Professor, Department of Mathematics and Information TechnologyAwards: Gold Medal, Organiser’s Choice Award

    A mobile app which uses augmented reality technology to help students learn English vocabulary. The app contains several learning modes and encourages users to practise and expand their English vocabulary through the gamified in-app activities.

  2. Audio-Tactile Chinese Characters: Bringing Multisensory & Novel Learning Experience to the Visually Impaired
    Principal investigator: Dr Hung Keung, Associate Professor, Department of Cultural and Creative ArtsAwards: Gold Medal, Best 10 Invention Designs Award

    A multi-sensory learning kit tailor-made for learners with visual impairment. It helps users understand the structural formation of Chinese characters and appreciate the beauty of traditional Chinese calligraphy through feeling, touching and hearing.

  3. Tree Assessment for Life Education (TALE) Project
    Principal investigator: Professor Jim Chi-yung, Department of Social Sciences, and Professor John Lee Chi-kin, Vice President (Academic) and ProvostAwards: Gold Medal, International Special Award

    A project which aims to raise public awareness of urban tree preservation and to cultivate users’ appreciation of life and other species. A mobile app is developed to facilitate learning of basic botanical knowledge and help users conduct tree assessments using the Visual Tree Assessment technique. The app also gathers georeferenced data which can be used for research and environmental education purposes.

  4. The Chinese Inventory of Children’s Socioemotional Competence (CICSEC)
    Principal investigator: Professor Kevin Chung Kien-hoa, Department of Early Childhood Education (ECE) and Dr Ian Lam Chun-bun, Associate Professor at ECEAwards: Silver Medal, International Special Award

    An evidence-based assessment system which can quickly evaluate children’s level of socioemotional competence. It is the first culturally responsive assessment system developed in Asia, targeting Chinese children. The CICSEC is also a conceptual framework and reliable indicator which can be easily used by kindergarten teachers.

  5. Dramaflow – Ideas Generation Dice for Planning Process Drama Lessons
    Principal investigator: Dr Pansy Tam Po-chi, Assistant Professor at ECEAwards: Bronze Medal, Best 10 Woman Inventors Award

    A toolkit equipped with design strategies to assist teachers in developing compelling Process Drama (PD) lessons for the early childhood education curriculum. Since most PD class activities rely on picture book storytelling, this toolkit encourages teachers to break out from the confined narratives and look for innovative ways to retell a story. As a creativity booster, it helps teachers overcome creative blocks and stimulate active exploration and imagination of PD class activities to achieve teaching objectives.

JC Thammasat organized an academic discussion on the Emergency Decree No. 27

The Faculty of Journalism and Mass Communication, Thammasat University organized an academic discussion on the Emergency Decree No. 27 “When people’s fear is a threat for government’s eyes” to provide knowledge on media and communication on issues related to news presentations in accordance with the Emergency Decree, No. 27, Section 9. Assoc.Prof. Kalyakorn Worakullattanee, Dean of the Faculty of Journalism and Mass Communication gave an opening speech. The attending lecturers and specialists consist of Asst. Prof. Dr. Wilaiwan Chongwilaikasem from the Faculty of Journalism Thammasat University, Assoc. Prof. Ruj Komolbut from the Faculty of Journalism Thammasat University, Yingcheep Atchanon, representative from iLaw, Ajarn Surasak Bunyanukunkit from the Faculty of Law Thammasat University and Ms. Supinya Klangnarong, co-founder of Cofact Thailand.

Assoc. Prof. Ruj Komolbut, Lecturer at Faculty of Journalism and Mass Communication, Thammasat University said that the Covid-19 situation urged the government to enforce the Royal Decree on Public Administration in Emergency Situations which 28 measures had been announced. The Regulation No. 1 and 27 mention the prohibition of dissemination of information, which brought up this discussion. In summary, the main point of the Regulation No. 1 is the dissemination of false news that incite fear in the public and misunderstanding in emergency situations. Authorities have the power to give a warning, suspend and adjust information and can be prosecuted under the Computer Crime Act if such news is not true and causes fear and the authorities can order to suspend and can take legal action. Regulation No. 27 contains different condition from No. 1 which is if the information is true but contains statement that may cause fear, it could be considered a violation.

“Based on the timeline, on July 10, 2021, Regulation No. 27 was announced. Two days later, the Deputy Prime Minister said that if the information is a fact, it can be presented. Three days later, the professional media organizations issued a statement to review these regulations because there was a discretionary issue, e.g. fear. Subsequently, Regulation No. 28 was announced then most people called out. After that the government issued the statement that the movement of artists and influencers is illegal. Thus, this meeting discussed how the regulations had the social and communicative effects.”

Ajarn Surasak Bunyanukunkit, Lecturer at Faculty of Law, Thammasat University stated that he would like to point out the Regulation No. 27, item 11, the restriction of freedom of expression and freedom of mass communication. The enforcement of the Royal Decree on Public Administration in Emergency Situations authorized the Prime Minister special powers in issuing requirements to deal with problematic situations. Regulation No. 1 and 27 had caused the issue on right and freedom restriction. The provision of Regulation No. 27 is too broad and may cause problems in interpretation because due to the vague provision, the terms can be applied to matters not directly related to the COVID-19 situation. This is to prohibit comments on government administration. Technically, the issuance of requirements should be adapted to the situation but such requirements are copied from the Emergency Decree which is too broad and can be interpreted in many ways. The provision has not yet clearly defined the scope, channels of dissemination, which refers to disseminate in “any other media” that may include social or digital media. The main point and issue is the term “contains message that incite fear” without specifying that such statement is a false or a true.

“Words with a broad meaning can mean true or false statement. The legislation for emergency situations should not contain broad wording which could lead to more distortion of the law. Such measures may be used to create a monopoly on information or to block information that the government would not like to reveal. The effect of the provisions shows that the government has chosen criminal measures to deal with personal opinions about the situation.”

Asst. Prof. Dr. Wilaiwan Chongwilaikasem, Lecturer of the Faculty of Journalism and Mass Communication Thammasat University said that in the current situation, government should explain and make people understand the situation. During the past 2 weeks, the Prime Minister has made fewer clarifications to the public. After clarification, the people felt that it was not clear at all. Instead, government tried to censor the public opinions. The regulation enforced by the government which had constantly threatening people. It can be defined that this situation is about how government managed their fear by regulating the law of media in the digital age. For the Regulation No. 28, although the media has not had any comment yet, but I believed that the editorial might proceed with the content censorship to avoid such issue. “The regulations enforced by the government have frightened both the media and the public reflects that the voice of people is also loud and powerful. Three days ago, people called out with fake news issue. We could tell that the government’s act was unsuccessful. In the past, when the revolution was about to happen, the media were invited to listen the guidelines of news presentation. Recently. Influencers were also invited to participate after the issuance of the Regulation No. 28.”