Employees of Samara Polytech have developed methods for constructing structural blocks for the creation of molecular ensembles with controlled molecular architecture. This enables to obtain functional materials and to control their physical, chemical and operational properties.
Scientists of the Department of Organic Chemistry of Samara Polytech have developed approaches to synthesize 1,3,6-tri- and 1,3,6,6-tetrasubstituted adamantane derivatives with a fundamentally new configurationally deterministic vector of cage substituents as a molecular basis for previously unknown tri- and tetrapoid systems. The latest research results are published in the “Russian Journal of Organic Chemistry” (DOI: 10.31857/S0514749220080108).
“One of the main tasks of modern organic synthesis is the development of new methods for obtaining complex molecules based on simple and polyfunctional structures. The key problem is the choice of available substrates with great preparative properties”, Elena Ivleva, Candidate of Chemistry, associate professor of the department explains.
“Polyfunctional adamantane derivatives containing substituents at the nodal and bridging positions of the cage fully satisfy these conditions, but, at the same time, are difficult to be obtained. This study made it possible to solve the problem of increasing the synthetic availability of 1,3,6-, 1,4,4- and 1,3,6,6-polyfunctional adamantane derivatives in order to use them as a substrate base in the creation of new functional materials.
Thus, a research team led by the head of the department, professor Yuri Klimochkin synthesized a number of new 1,3,6-, 1,4,4-tri- and 1,3,6,6-tetrasubstituted polyfunctional derivatives of the cage structure on the basis of bridged carboxylic acids of the adamantane series. The resulting compounds enable to obtain the new generation of functional materials.